At theBJUIthe best things in life are free

Few things in life are "free": cellular uptake of steroid hormones by an active transport mechanism.

Conventional dogma holds that steroid hormones traverse cell membranes passively, owing to their lipophilic nature. The recently characterized protein megalin, however, functions as a transport protein on cell surfaces to carry steroids across the plasma membrane. Upon hydrolysis of steroid-associated binding globulins in lysosomes, free hormone is liberated and may exert its effects in the cel...

Free Will and Agency at Its Best

[Best things in the worst times].

The best things in the worst times that we provide for you will be ultimate to give preference. This reading book is your chosen book to accompany you when in your free time, in your lonely. This kind of book can help you to heal the lonely and get or add the inspirations to be more inoperative. Yeah, book as the widow of the world can be very inspiring manners. As here, this book is also creat...

Bilattices Are Nice Things

One approach to the paradoxes of self-referential languages is to allow some sentences to lack a truth value (or to have more than one). Then assigning truth values where possible becomes a fixpoint construction and, following Kripke, this is usually carried out over a partially ordered family of three-valued truth-value assignments. Some years ago Matt Ginsberg introduced the notion of bilatti...

securitization of mortality risks in life annuities

insurers have in the past few decades faced longevity risks - the risk that annuitants survive more than expected - and therefore need a new approach to manage this new risk. in this dissertation we survey methods that hedge longevity risks. these methods use securitization to manage risk, so using modern financial and insurance pricing models, especially wang transform and actuarial concepts, ...